DAYA HAMBAT BAKTERI Staphylococcus aureus EKSTRAK DAUN GAHARU (Aquilaria malea L.) SEBAGAI ANTIBAKTERI

  • Abdul Rahman Wahid Universitas Muhammadiyah Mataram
  • Dzun Haryadi Ittiqo Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Mataram
Keywords: Aquilaria malea L., Inhibition, Staphyloccus aureus

Abstract

Aquilaria malea L. are spread naturally in several countries, one of them in Indonesia. This plant has many benefits ranging from stems and leaves. Agarwood leaves contain various antibacterial compounds such as flavonoids, alkaloids, saponins and tannins. Staphylococcus aureus is a facultative anaerobic gram-positive bacterium which is the cause of infection in wounds in the form of abscesses or a collection of pus. The study aims to determine the inhibitory strength of Staphylococcus aureus bacteria extract of aloes leaves as anti-bacterial. This type of research is laboratory experimental through the disc diffusion method. The concentration of agarwood leaves used is 300, 350, 400, and 450 mg/ml and positive control Amoxicillin. Data were analyzed using One Way Annova. The results of this study showed the average inhibition zone of agarwood leaf extract against Staphylococcus aureus bacteria with agarwood leaf extract concentration of 300 mg/ml (15.33 ± 2.51), concentration of 350 mg/ml (16.33±2.25), concentration of 400 mg/ml (20.5± 2.17), concentration of 450 mg/ml (21.17±3.32) and inhibition zone of Amoxicillin (37±0.00). This concluded that agarwood leaf extract had inhibitory potential for the growth of Staphylocccus aureus bacteria. The biggest inhibition power of Staphyloccus aureus growth was 450 mg/ml (21.17 ± 3.32).

References

Rostinawati, T., 2009, Aktivitas Antibakteri Ekstrak Etanol Bunga Rosella (Hibiscus Sabdariffa L.) Terhadap Escherichia Coli, Salmonella Typhi Dan Staphylococcus Aureus Dengan Metode Difusi Agar, Penelitian Mandiri : Fakultas Farmasi, Universitas Padjajaran.

World Health Organization, 2012, https://www.who.int/gho/publications/world_health_statistics/EN_WHS2012_Full.pdf.

World Health Organization, 2012, https://www.who.int/gho/publications/world_health_statistics/EN_WHS2012_Full.pdf.

Anonim. 2010. Statistik Kehutanan Indonesia: Planologi Kehutanan (Forestry Planning). Departemen Kehutanan. Jakarta.

Khalil, A. S., Rahim, A. A., Taha, K.K., Abdallah K. B. 2013. Chacacterizatio of Methanolic Extracts of Agarwood Leaves.Journal of Applied and Industrial Sciences.1 : 78-88.

Sheikh, M., Abdullah R.M., M.K., Meghavanshi and Irshad, M. 2012, Studies on Some Plant Extract for Their Antimicrobial Potential Against Certain Pathogenic Microorganisms. American Journal of Plant Sciences. 3.

Kamonwannasit,C., Nantapong, N., Kumkrai, P., Luecha, P.,Kupittayanant dan Chudapongse, N. 2013. Antibacterial Activity of Aquilaria crassna Leaf Extract Against Staphylococcus epidermidis by Disruption of Cell Wall. Annals of Clinical Microbiology and Antimicrobials. 7 p.

Aisyah. 2015. Inhibition Power of Pandan Wangi Extract (Pandanus amaryllifolius Roxb.) Against Staphylococcus aureus Bacterial Growth. Faculty of Dentistry, Hasanuddin University.

Harbone, J.B. 1987. Phytochemical Methods Guides Modern Ways to Analyze Plants Translated by Kosasih Padmawinata and Imam Sudiro, Edition I, 9-10 ITB. Bandung.

Larra, Sofhy W. 2014. Antibacterial Activity Test of Cabbage I Extract (Brassia aleracea L. var. Capitata L.) Against Escherichia coli Bacteria Hidayatullah Syarif State Islamic University. Jakarta.

Bobbarala, V. 2012. Antimicrobial Agents.Intech, Croatia

Harbone, J.B. 1996. Phytochemical Method. translated by Kosasih Padmawinata and Iwan Soediro Edition II, hal 14; 21-22; 69; 72, ITB Press, Bandung.

Greenwood, 1995, Antibiotics Susceptibility (Sensitivity) Test, Antimicrobial ant Chemoteraphy. Addison Wesley Longman INE, San Frasisco, USA.

Published
2019-05-29
How to Cite
1.
Wahid A, Ittiqo D. DAYA HAMBAT BAKTERI Staphylococcus aureus EKSTRAK DAUN GAHARU (Aquilaria malea L.) SEBAGAI ANTIBAKTERI. JIFI [Internet]. 29May2019 [cited 24Oct.2019];2(1):34-3. Available from: http://jiis.akfar-isfibjm.ac.id/index.php?journal=JIFI&page=article&op=view&path[]=299
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Articles