POTENSI KOMBINASI KAPUR SIRIH DAN DAUN KUMPAI MAHUNG (Eupatorium inulifolium H.B&K.) SEBAGAI ALTERNATIF SALEP ANTI INFLAMASI ALAMI

  • Dwi Rizki Febrianti Akademi Farmasi ISFI Banjarmasin
  • Siska Musiam Akademi Farmasi ISFI Banjarmasin
Keywords: combination, imflamation

Abstract

Kumpai Mahung (Eupathorium inulifolium H.B & K) is one of an endemic plant in South Kalimantan. Hereditary used as traditional medicine. kapur sirih (calcium carbonate) is also used by the community as a food additive (BTP), especially in the manufacture of chips and fruit ice. Traditionally these two ingredients are combined to treat swollen (oedema) mastitis in nursing mothers. This research method using raw test pad oedema in legs male rats. simple ointment dosage form, induction carrageenan 3% and hydrocortisone as a positive control anti-inflammatory calculated the value and the value AUC (area under the curve). the results expressed Ointment combination Kumpai Mahung  leaf extract and calcium carbonate have anti-inflammatory power of 14.91% greater than the positive control 9.95%.

References

Bernardi A Zilberstein A Jäger E Campos M Morrone F Calixto J Pohlmann A Guterres S Battastini A, 2009, Effects Of Indomethacin-Loaded Nanocapsules In Experimental Models Of Inflammation In Rats, British Journal Of Pharmacology, Doi 10.1111/J.1476-5381.2009.00244.Xr Niah, 2018

Febrianti Dwi Rizki,Eka Kumalasari, Via Oktaviani, 2019, Potensi Kombinasi Ekstrak Daun Belimbing Wuluh (Averrhoa Bilimbi L.) Dengan Amoksisilin Terhadap Staphylococcus Aureus, Borneo Journal Of Pharmascientech Vol 3 No 1, 94-100

Febrianti, Dwi Rizki (2018) ‘Analisis Kandungan Flavonoid Dan Aktivitas Antihiperurisemia Ekstrak Etanol Daun Sirsak (Anona Muricata L.) Pada Mencit Jantan Secara In Vivo’, Jurnal Ilmiah Ibnu Sina, 3(Oktober 2018), Pp. 304–311.

Isrofah, Sagiran And Afandi, M. (2011) ‘Efektifitas Salep Ekstrak Daun Binahong (Anredera Cordifolia (Ten) Steenis) Terhadap Proses Penyembuhan Luka Bakar Derajat 2 Termal Pada Tikus Putih (Rattus Novergicus)’, Muhammadiyah Journal Of Nursing, Pp. 99–108.

Karnad, A. S., Patil, P. A. And Majagi, S. I. (2006) ‘Calcium Enhances Antiinflammatory Activity Of Aspirin In Albino Rats’, Indian Journal Pharmacol, 38(6), Pp. 397–402.

Mochammad Maulidie Alfiannor Saputera, Noverda Ayuchecaria, 2018, Uji Efektivitas Ekstrak Etanolik Batang Bajakah Tampala (Spatholobus Littoralis Hassk.) Terhadap Waktu Penyembuhan Luka, Jurnal Ilmiah Ibnu Sina 3(2), 318-327

Noorcahyati., 2012, Tumbuhan Berkhasiat Obat Etnis Asli Kalimantan. Balikpapan Kalimantan Timur:Balai Penelitian Teknologi Konservasi Sumber Daya Alam.

Rakhmadhan Niah, Dwi Rizki Febrianti, 2018, Optimasi Ekstrak Daun Karamunting (Melastoma Malabathricum L.) Dari Berbagai Pelarut Sebagai Antibakteri Tifoid, Jurnal Insan Farmasi Indonesia (1)2, 191-200

Rosa Julia Salvan Da, Silvana Virginia Gagliotti Vigil De Mello, Geison Vicente, Yeo Jim K. Moon, Felipe Perozzo Dalto, Tamires Cardoso Lima, Rafaela De Jesus Souza, 2017, Calea Uniflora Less. Attenuates The Inflammatory Response To Carrageenan-Induced Pleurisy In Mice, International Immunopharmacology 42 (2017) 139–149, Doi.Org/10.1016/J.Intimp.2016.11.029.

Sousa Orlando Vieira De, Glauciemar Del-Vechio Vieira, José De Jesus R. G. De Pinho, Célia Hitomi Yamamoto, Dan Maria Silvana Alves, 2010, Antinociceptive And Anti-Inflammatory Activities Of The Ethanol Extract Of Annona Muricata L. Leaves In Animal Models, International Journal Of Molecular Sciences, Vol 11, Hal 2067-2078.

Tran, M.H., To, D. C., Nguyen, H.D., 2011, Flavonoid Glycoside From Chromolaena Odorata Leaves And Their In Vitro Cytotoxic Activity, Journal Of Chem Pharm. Bull. 59(1) 129-131.

Widji Soeratri, Tristiana Erawati, Diny Rahmatika, N. R. (2014) ‘Penentuan Dosis Asam P-Metoksisinamat (Apms) Sebagai Antiinflamasi Topikal Dan Studi Penetrasi Apms Melalui Kulit Tikus Dengan Dan Tanpa Stratum Korneum’, Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 1(1), Pp. 28–30.

Published
2019-10-31
How to Cite
Febrianti, D., & Musiam, S. (2019). POTENSI KOMBINASI KAPUR SIRIH DAN DAUN KUMPAI MAHUNG (Eupatorium inulifolium H.B&K.) SEBAGAI ALTERNATIF SALEP ANTI INFLAMASI ALAMI. Jurnal Ilmiah Ibnu Sina, 4(2), 323-330. https://doi.org/10.36387/jiis.v4i2.339
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Artikel